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Greater Suicide Risk With Varenicline vs Other Cessation Meds

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Greater Suicide Risk With Varenicline vs Other Cessation Meds

Post  Admin on Wed Nov 02, 2011 7:05 pm

Greater Suicide Risk With Varenicline vs Other Cessation Meds
No Place for Agent as First-Line Treatment, Researchers Say
Deborah Brauser
From Medscape Medical News


Investigators found that 90% of the reports of self-injurious behavior or depression were associated with the use of varenicline. Bupropion and nicotine replacement products were responsible for the remaining 7% and 3%, respectively.

The FDA concludes: "Moore et al's conclusion that 'varenicline shows a substantial, statistically significant increased risk of reported depression and suicidal/self-injurious behavior' is misleading, as [proportional reporting ratios] are measures of association and not measures of risk,".

Read the article here:
Medscape Medical News


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