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SSRIs Mechanism: Side Effects Vs Therapeutic Action Vs Tolerance

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SSRIs Mechanism: Side Effects Vs Therapeutic Action Vs Tolerance

Post  Admin on Sun Jan 22, 2012 4:56 pm

Mechanism of Action of SSRIs (Selective Serotonin Reuptake Inhibitors)

Q1. Why Side effects appear earlier during treatment with SSRIs?
Q2. Why SSRIs takes 3-4 weeks to have therapeutic benefit?
Q3. How does tolerance develops to SSRIs side effects?

We should first understand the basic structure & function of serotonin neuron (esp the role of 5HT1A autoreceptors):

Now check below for the answers for above 3 questions:


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