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Drug- Drug Interactions & CYP450 Enzyme

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Drug- Drug Interactions & CYP450 Enzyme

Post  Admin on Mon May 02, 2011 3:57 am

Match the following drug interactions with responsible CYP450 enyme

(1) Fluvoxamine + Theophylline =Raises Theophyline
(2) Fluvoxamine + Cisapride = Raised QT Interval
(3) Nefazodone + Alprazolam = Raises Alprazolam
(4) TCAs + SSRIs =Raises TCAs
(5) Fluozetine + Triazolam = Raises Triazolam
(6) Carbamazepine Autoinduction
(7) Imipramine + Smoking= Decreases Imipramine level


(a) CYP450 1A2
(b) CYP450 2D6
(c) CYP450 3A4





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