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Which of the Following Antidepressant is Most Effective in Treatment of Premature Ejaculation?

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Which of the Following Antidepressant is Most Effective in Treatment of Premature Ejaculation?

Post  Admin on Sun Jul 22, 2012 4:35 pm



Q.1: Which of the following antidepressant is most effective in treatment of premature ejaculation?
(a) Fluoxetine
(b) Clomipramine
(c) Paroxetine
(d) Sertraline
(e) Citalopram


Q.2: Which of the following medications doses may be successful in reversing SSRI induced sexual dysfunction?
(a) Bupropion 150 mg, Buspirone 20 mg
(b) Bupropion 300 mg, Buspirone 20 mg
(c) Bupropion 150 mg, Buspirone 60 mg
(d) Bupropion 300 mg, Buspirone 60 mg

Goodluck


Last edited by Admin on Wed Sep 19, 2012 9:34 pm; edited 1 time in total

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Re: Which of the Following Antidepressant is Most Effective in Treatment of Premature Ejaculation?

Post  perox123 on Wed Sep 19, 2012 9:03 pm

Q1. (a) Fluoxetine

Q2. (d) Bupropion 300 mg, Buspirone 60 mg

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Re: Which of the Following Antidepressant is Most Effective in Treatment of Premature Ejaculation?

Post  Admin on Wed Sep 19, 2012 9:51 pm

Admin wrote:

Q.1: Which of the following antidepressant is most effective in treatment of premature ejaculation?
(a) Fluoxetine
(b) Clomipramine
(c) Paroxetine
(d) Sertraline
(e) Citalopram


Ans: (C) Paroxetine

At daily treatment, the overall efficacy of 20mg paroxetine, 50–100mg sertraline, 20–40mg citalopram, 20-40mg Fluoxetine and 10–20mg clomipramine is comparable, but paroxetine exerts the strongest ejaculation delay.
Source: Int J Impot Res. 2004 Aug;16(4):369-81.



Admin wrote:

Q.2: Which of the following medications doses may be successful in reversing SSRI induced sexual dysfunction?
(a) Bupropion 150 mg, Buspirone 20 mg
(b) Bupropion 300 mg, Buspirone 20 mg
(c) Bupropion 150 mg, Buspirone 60 mg
(d) Bupropion 300 mg, Buspirone 60 mg

Ans: (D) Bupropion 300 mg, Buspirone 60 mg

It have been established that Buspirone 60mg daily will reverse SSRI induced sexual dysfunction in both sexes, failure reported at lower doses
Source: Landen et al 1999
Buspirone 300mg effective & 150mg not effective.
Source: Clayton et a;, JCP 2004

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