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Toxoplasma gondii Immunoglobulin G Antibodies and Nonfatal Suicidal Self-Directed Violence

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Toxoplasma gondii Immunoglobulin G Antibodies and Nonfatal Suicidal Self-Directed Violence

Post  Admin on Sun Aug 12, 2012 6:46 pm

Toxoplasma gondii Immunoglobulin G Antibodies and Nonfatal Suicidal Self-Directed Violence
J Clin Psychiatry- Online ahead of print: July 10, 2012



The primary aim of this study was to relate Toxoplasma gondii seropositivity and serointensity to scores on the self-rated Suicide Assessment Scale (SUAS-S).
Another aim was to reevaluate the previously reported positive association between T gondii serointensity and a history of nonfatal suicidal self-directed violence.

Method:
This cross-sectional, observational study compared T gondii serointensity and seropositivity in plasma from 54 adult suicide attempters (inpatients at Lund University Hospital, Lund, Sweden) and 30 adult control subjects (randomly selected from the municipal population register in Lund, Sweden) recruited between 2006 and 2010.

Results:
Seropositivity of T gondii was associated with higher SUAS-S (Suicide Assessment Scale Self-report version) scores, a relationship significant for the whole sample (P = .026), but not for suicide attempters only.
No significant associations with other pathogens (cytomegalovirus, and herpes simplex virus type 1) were identified.

Conclusions:
These results are consistent with previous reports on the association between T gondii infection and nonfatal suicidal self-directed violence. Confirming these results in future large longitudinal studies and including suicide as an outcome may lead to novel individualized approaches in suicide prevention.


Note: Similar study details on "Relationship Between Toxoplasma Gondii Infection and Mood Disorders " was posted on our forum few months ago:
Check out this link: bit.ly QUoZAK

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