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Efficacy of Antipsychotics in Pediatric Acute Mania

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Efficacy of Antipsychotics in Pediatric Acute Mania

Post  Admin on Wed Jun 22, 2016 8:46 pm

Efficacy of Antipsychotics in Pediatric Acute Mania



Important information to consider while prescribing antipsychotics for pediatric mania. This table compares NNT (Number Needed to Treat) and NNH (Number Needed to Harm) for each antipsychotics.

ANTIPSYCHOTICS:    NNT     NNH
(a) Risperidone:          3         16
(b) Aripiprazole:          4         29
(c) Olanzapine:          4         3
(a) Ziprasidone:          4         34
(d) Quetiapine:          5         9
(e) Asenapine:          3         12
Note: Ziprasidone is not FDA approved for this indication.

Source: Ketter TA, editor. Advances in the Treatment of Bipolar Disorder. Arlington, VA: APA Publishing; 2015.

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